Drug Seizures at the U.S. Border

U.S. Customs and Border Protection seized 1.9 million pounds of drugs in 183,003 seizure events between FY2023 and FY2026. The deadliest: 65,123 pounds of fentanyl — enough for an estimated 14.8 billion lethal doses.

65.1K lbs
Fentanyl Seized
542K lbs
Methamphetamine
243K lbs
Cocaine
97.5%
Via Southwest Border
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The Fentanyl Crisis

Fentanyl is 50-100x more potent than morphine. Just 2 milligrams — the weight of a few grains of salt — can be lethal. The 65,123 lbs seized by CBP represents roughly 14.8 billion potential lethal doses. In FY2023 alone, 27,023 lbs were intercepted.

Fentanyl was involved in approximately 75,000 U.S. overdose deaths in 2023, making it the leading cause of death for Americans ages 18-45. Most illicit fentanyl enters through the southwest border, primarily at official ports of entry hidden in vehicles and commercial shipments.

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Key Insights

97.5% of fentanyl comes through the southwest border — primarily at official ports of entry, not between them
Fentanyl seizures peaked in FY2023 at 27,023 lbs — volumes are declining as enforcement tightens
Methamphetamine is the largest by weight at 542K lbs — but fentanyl is far deadlier per pound
Heroin seizures collapsed to 4.7K lbs — fentanyl has largely replaced heroin in the drug supply

Fentanyl Seized by Year (lbs)

Total Seizures by Drug Type

Drug Seizures by Type (lbs)

Top Fentanyl Seizure Locations

Drug Seizures by Type (FY2023-2026)

DrugSeizure EventsPounds Seized% of Total Weight
Marijuana73,228589,56331.0%
Methamphetamine10,452542,23128.5%
Other Drugs77,314288,85615.2%
Cocaine7,832242,95312.8%
Khat (Catha Edulis)516138,0147.3%
FentanylDeadliest3,66165,1233.4%
Ketamine3,71627,7361.5%
Heroin1,1084,7380.2%
Ecstasy3,9711,7430.1%
Lsd1,205400.0%

Fentanyl Seizures by Year

Fiscal YearSeizure EventsPounds SeizedEst. Lethal Doses
FY20231,35127,0236.13B
FY20241,11621,8894.96B
FY202595912,0272.73B
FY2026 (FYTD)2354,1830.95B

Top Fentanyl Seizure Locations

#Area of ResponsibilityPoundsEvents
1TUCSON FIELD OFFICE30,378730
2SAN DIEGO FIELD OFFICE23,6481,124
3SAN DIEGO SECTOR2,854140
4TUCSON SECTOR2,388273
5YUMA SECTOR1,70149
6EL PASO FIELD OFFICE1,046282
7EL CENTRO SECTOR678172
8CHICAGO FIELD OFFICE621182
9LAREDO FIELD OFFICE47464
10HOUSTON FIELD OFFICE3195

How Drugs Cross the Border

Contrary to popular perception, the majority of hard drugs — especially fentanyl and cocaine — enter the United States through official ports of entry, not between them. Drug traffickers hide narcotics in passenger vehicles, commercial trucks, and cargo shipments passing through CBP inspection at legal border crossings.

U.S. Border Patrol (operating between ports) seizes more marijuana, while the Office of Field Operations (at ports of entry) intercepts the majority of fentanyl, meth, and cocaine. This distinction matters for policy: border walls primarily affect between-port crossings, while drug interdiction depends on scanning technology, intelligence, and inspection capacity at the ports themselves.

The Fentanyl Supply Chain

Most illicit fentanyl is manufactured in Mexico using precursor chemicals sourced primarily from China. Mexican cartels — primarily the Sinaloa Cartel and Jalisco New Generation Cartel (CJNG) — operate large-scale production labs and smuggle finished product across the southwest border.

Fentanyl is extremely profitable to smuggle because of its potency-to-weight ratio. One kilogram of fentanyl can generate $1-2 million in street revenue, compared to $25,000-$50,000 for a kilogram of heroin. This economics has driven the near-complete replacement of heroin with fentanyl in the U.S. drug supply — visible in our data as heroin seizures plummeted while fentanyl surged.

Seizures vs. Flow

CBP estimates it intercepts only a fraction of total drug flow. Seizure data tells us what wascaught, not what crossed. Increases in seizures can indicate either more drugs flowing or better detection capabilities — often both simultaneously.

Source: U.S. Customs and Border Protection Drug Seizure Statistics. Data through January 2026. Lethal dose estimates based on DEA figure of 2mg as potentially lethal.